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What it does not establish is that this process is ever visible to the naked eye as a temporary worsening in normal, healthy skin outside a wound-healing context, or that it happens in a way tied to dose or frequency of use

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The new concept implicates reduced ceruloplasmin ferroxidase activity, which is typically low in Wilson disease, resulting in decreased circulating iron and increased hepatic iron storage [132]

Glutathione also serves as a key factor in proper detoxification.