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GPx-1 and genetic polymorphisms The human GPx-1 gene localizes to human chromosome 3p21, a region that has been associated with loss of heterozygosity (LOH), a process that involves deletion of a chromosomal region from one of two autosomes leading to the detection of only one allelic variant in individuals who are (in all other tissues) heterozygous

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It drives two enzyme reactions that matter clinically

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