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The effects become visible within four weeks, and the significant effects may need a maximum of three months

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With high antigen-presenting capacity, they secrete reactive oxygen species (ROS) and proinflammatory cytokines, including IL-1, IL-6, IL-12, IL-18, IL-23, and TNF-α, which modulate Th1-mediated antigen-specific inflammatory responses (85, 86)

an important neurotransmitter for brain and nerve cell function