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Dysregulated glutamine metabolism in cancer cells facilitates the synthesis of macromolecules (proteins, nucleotides, and lipids), oxidative stress/redox homeostasis, epigenetic functions, and anabolic processes crucial for sustaining cancer cells’ rapid proliferation and survival [22]

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W 1921 Frederick Hopkins zasugerował, że filotion wyizolowany z wątroby, mięśni szkieletowych i drożdży jest dipeptydem składającym się z cysteiny i glutaminianu