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Cagrilintide produces dose-dependent weight loss and improvements in glycemic control in clinical trials, and it has shown particularly impressive results when combined with GLP-1 receptor agonists, suggesting synergistic effects between amylin and incretin pathways

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Hence, in the spleens CD4 + FoxP3 + Tregs were increased, while proarthritic Th1 (CD4 + Tbet + ) and Th17 (CD4 + RORγt + ) were decreased (Supplementary Fig

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