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It ends up being a malignant mass that had they waited six months, they would have, you know, had stage four pancreatic cancer and passed away

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On the other hand, double Ghr ko/ Igf1 ko resulted in further postnatal growth retardation relative to Igf1 ko mice completely obstructing further weight gain after postnatal day 15 and supporting previous studies suggesting that progenitor cells in the growth plate require direct GH actions (24)