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They will likely want to: Review your complete medication list to identify potential interactions with other drugs you are taking Assess your diabetes status and current glycaemic control if you have type 2 diabetes Evaluate your tolerance of Wegovy to date, particularly regarding gastrointestinal side effects Discuss your treatment goals and whether berberine is likely to provide meaningful additional benefit Establish a monitoring plan if you proceed with the combination For people with type 2 diabetes and existing diabetic retinopathy, healthcare professionals may recommend appropriate eye monitoring when starting treatments that can rapidly improve glycaemic control, as this can sometimes temporarily worsen retinopathy