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In clinical trials at the 12 mg dose, researchers documented nausea in 28% of participants, diarrhea in 23%, constipation in 17%, and vomiting in 12%

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Marked anisocytosis is often noted (reflected as a wide red blood cell size distribution on the electronic counter) because of the coexistence of large polychromatic cells and “contracted” cells, some of which can be frankly classified as spherocytes