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Initial Glutathione Depletion During Short-Term Bed Rest: Pinpointing Synthesis and Degradation Checkpoints in the γ-Glutamyl Cycle

Tripeptide-copper complexes raise vascular endothelial growth factor, which supports the blood supply feeding a follicle, and lower transforming growth factor-beta1, a signal associated with the follicle entering its regression phase [1]

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3.2 Iron dysregulation in modulating ferroptosis susceptibility Iron overload, as a key inducer of ferroptosis, disrupts cellular iron homeostasis by interfering with critical components of iron metabolism at both transcriptional and post-transcriptional levels, thereby significantly increasing cellular susceptibility to ferroptosis (59)