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Dietary requirements The daily requirement of vitamin B 12 has been set at 2.4 μg, but higher amounts — 4 to 7 μg per day — which are common in persons who eat meat or take a daily multivitamin, are associated with lower methylmalonic acid values

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This interaction increases intracellular cAMP levels and activates protein kinase A, triggering pulsatile release of endogenous growth hormone