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Regulation of CD8 + T cell-mediated immune responses by amino acid metabolism Glutamine Glutamine is deaminated to form glutamate and α-ketoglutarate (α-KG), which supports anaplerosis of the TCA cycle and plays a crucial role in regulating histone methylation and chromatin accessibility (Fig

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By desensitization, he means that the adrenals are not as responsive as they should be