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In this review, we have discussed the main discoveries regarding the physiological signaling functions of ROS in the cell and developmental processes of the invertebrate Drosophila and of mammalians including hematopoiesis, adult stem cells, tissue regeneration, and pluripotent stem cell biology, iPSCs generation, as well as systemic cell non-autonomous functions of ROS

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Additionally, supplements containing glutathione precursors, such as N-acetylcysteine (NAC) and alpha-lipoic acid, can support the body's natural production of this essential antioxidant