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hGH-receptor competition and hGH-receptor-dependent cell-proliferation endpoints in vitro, and beta3-adrenergic-receptor RNA and knockout-model endpoints in mouse models In vitro Animal model 3 Human pilot 4 RCT 5 Approval Evidence Research highlights AOD-9604 was examined in obese-mouse and beta3-adrenergic-receptor knockout mouse models using body-mass, tissue and receptor-RNA endpoints