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For researchers interested in the comparison between tirzepatide and next-generation compounds like retatrutide, which adds a third receptor (GCG), our guide to retatrutide versus semaglutide provides useful context, as does our three-way comparison of semaglutide, tirzepatide, and retatrutide

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Other than GI-related side effects, patients on semaglutide also report serious side effects, such as kidney problems, pancreatitis, gallbladder disease, hypoglycemia (low blood sugar), and severe allergic reactions

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