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Moreover, it has been shown that the presence of elesclomol-Cu in the mitochondria of cancer cells (MDA-MB-435 melanoma cell line and HL-60 leukemia cell line) can facilitate the redox cycling of copper and thus generate ROS [76]

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10.1016/j.neuroscience.2012.10.019 Neuroscience 113 LunenfeldB.BilgerW.LongobardiS.KirstenJ.D’hoogheT.SunkaraS