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CagriSema Storage & Handling Storage Reference Lyophilized (powder form) Cagrilintide -4°F (-20°C) long-term Semaglutide -4°F (-20°C) long-term Pre-blended CagriSema -4°F (-20°C) long-term Reconstituted (liquid form) Cagrilintide 35.6–46.4°F (2–8°C) Semaglutide 35.6–46.4°F (2–8°C) Pre-blended CagriSema 35.6–46.4°F (2–8°C) Appearance Cagrilintide Clear after reconstitution Semaglutide Clear after reconstitution Pre-blended CagriSema Clear after reconstitution Stability window after reconstitution Cagrilintide Up to ~28 days refrigerated Semaglutide Up to ~28 days refrigerated Pre-blended CagriSema Per supplier COA Always defer to the supplier's specific stability window

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doi: 10.1007/BF00591565