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Increased mitochondrial circularity is commonly associated with loss of mitochondrial membrane potential and mitochondrial dysfunction following APAP exposure (Umbaugh et al

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Composto por quatro aminoácidos (Ala-Glu-Asp-Gly), o Epithalon vem sendo investigado em modelos experimentais por sua possível influência em mecanismos ligados à atividade da telomerase e estabilidade dos telômeros , tornando-se um dos peptídeos mais estudados em protocolos científicos voltados à biologia do envelhecimento