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Administered as a once-weekly subcutaneous injection, tirzepatide is available in doses ranging from 2.5 mg to 15 mg, with recommended dose escalation in 2.5 mg increments approximately every 4 weeks to minimize gastrointestinal side effects

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A 5mg nasal dose delivering 1.5–2mg systemic exposure is not interchangeable with a 2mg injectable dose delivering 1.9–2mg systemic exposure